--- title: Facilitate proper absorption of acid-resistant Caps | CapsCanada description: "In order to protect probiotics and encourage their absorption, the best solution are acid-resistant capsules: learn everything about this technology." image: https://blog.lyfegroup.com/hubfs/acid-resistant%20capsules-1.jpg --- [![Logo-LyfeGroup-blue](https://blog.lyfegroup.com/hs-fs/hubfs/Logo-LyfeGroup-blue.png?width=800&height=169&name=Logo-LyfeGroup-blue.png)](https://blog.lyfegroup.com/) [![Logo-LyfeGroup-blue](https://blog.lyfegroup.com/hubfs/Logo-LyfeGroup-blue.png)](https://blog.lyfegroup.com/) - [Company](https://capscanada.com/company/?_gl=1*lcqm70*_gcl_au*NjgyNjM5Njk4LjE3Mzc0OTIzMzI.) - [Contact](https://capscanada.com/contact/?_gl=1*lcqm70*_gcl_au*NjgyNjM5Njk4LjE3Mzc0OTIzMzI.) - [Jobs](https://capscanada.com/careers/?_gl=1*lcqm70*_gcl_au*NjgyNjM5Njk4LjE3Mzc0OTIzMzI.) - [Industries](https://capscanada.com/markets/) - [Pharmaceutical](https://capscanada.com/pharmaceuticals/) - [Nutraceutical](https://capscanada.com/nutraceuticals/) - 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We have a new image, but the same team, products and quality as always. | CapsCanada is now Lyfe Group. We have a new image, but the same team, products and quality as always. | CapsCanada is now Lyfe Group. We have a new image, but the same team, products and quality as always. | CapsCanada is now Lyfe Group. We have a new image, but the same team, products and quality as always. | CapsCanada is now Lyfe Group. We have a new image, but the same team, products and quality as always. | CapsCanada is now Lyfe Group. We have a new image, but the same team, products and quality as always. | CapsCanada is now Lyfe Group. We have a new image, but the same team, products and quality as always. | CapsCanada is now Lyfe Group. We have a new image, but the same team, products and quality as always. | CapsCanada is now Lyfe Group. We have a new image, but the same team, products and quality as always. | ![How to facilitate proper absorption of acid-resistant Capsules](https://blog.lyfegroup.com/hubfs/acid-resistant%20capsules%201.jpg "How to facilitate proper absorption of acid-resistant Capsules") - [AR-CAPS®](https://blog.lyfegroup.com/tag/AR-CAPS) # Probiotics and acid-resistant capsules: how to facilitate proper absorption Posted by [CapsCanada](https://blog.lyfegroup.com/author/capscanada) on Feb 5, 2021, 9:00:00 a.m. Many people take probiotics as an extra measure to help their bodies get the nutrients they need for a healthier life. Technically, [the point of consuming a probiotic supplement is to introduce beneficial bacteria in the gut](https://my.clevelandclinic.org/health/articles/14598-probiotics#:~:text=Probiotics%20are%20made%20up%20of,and%20your%20body%20%E2%80%94%20your%20microbiome.). Unfortunately, probiotics and stomach acid don't always mesh well.  The body’s [naturally harsh stomach acid, needed to digest all kinds of food, kills off 99% of the probiotic](https://www.nytimes.com/2014/04/01/science/gut-reactions-to-beneficial-bacteria.html) strains from the major sources of probiotics long before these products can even get to the small intestine. So how do you get probiotics to cross the stomach and reach the intestine to grow and colonize, so the body can obtain the benefits they bring? The vast majority of probiotics die from the extreme conditions they face when reaching the stomach. Therefore, the best way to get them through is by encapsulating  them with an enteric coating or lining acting as a protective shield against gastric acids.  The [Canadian Society of Intestinal Research](https://badgut.org/information-centre/a-z-digestive-topics/pill-coating/) suggests that in order to protect probiotics and encourage their absorption, it is recommended to cover them with an enteric coating acting as a barrier over them, thus preventing the capsule or pill from dissolving in the stomach acid.   ## Formulation and coating-process issues   It is one thing to encapsulate probiotics with an enteric coating so they can pass through the stomach, but another is to produce a formulation that protects them and, most importantly, that allows for easy and effective absorption by the body.  [![gelatin capsules brochure](https://no-cache.hubspot.com/cta/default/7215323/a86c2e8b-555e-4f56-b80b-95e514ea0364.png)](https://cta-redirect.hubspot.com/cta/redirect/7215323/a86c2e8b-555e-4f56-b80b-95e514ea0364)   One of the best formulations for probiotic coating is hypromellose, a semi-synthetic polymer widely used in the Western Hemisphere for drug coating. Nevertheless, most enteric-coating processes all over the world are costly and complex, so it’s not just about the technology used, but also the entire coating process.  On the other hand, most probiotic coating formulations use added chemicals, solvents or other coatings to delay the release of the formulation as it passes through the digestive tract. Indeed, the capsule maintains its stability against stomach pH levels, but breaks down when it reaches the highest pH levels in the small intestine.   ***Keep learning about capsule technology trends...*** - [Gelatin capsules vs. HPMC capsules: What are the differences?](https://blog.capscanada.com/differences-between-gelatin-capsules-and-hpmc-capsules) - [Why Liquid-Filled Hard Capsules May Be a Better Option than Softgels](https://blog.capscanada.com/why-liquid-filled-hard-capsules-may-be-a-better-option-than-softgels) - [Flavored capsules: the next customization level](https://blog.capscanada.com/flavored-capsules-the-next-customization-level)   ## Reducing the processing complexity in a first-level product   Regardless of the formulation of the drug or probiotic to be coated, as in this case, it is essential to look for one bearing low moisture content, in order to make it moisture or hygroscopic sensitive. Additionally, it must feature the following properties: - Delayed release - Gastric-acid resistant  - Low moisture content - Cross-linking resistant - Stability over a wide temperature and humidity range - Wide regulatory acceptance for pharmaceutical applications   [![HPMC capsules](https://no-cache.hubspot.com/cta/default/7215323/b292138e-f940-4d8b-9b09-9923cbecd4d2.png)](https://cta-redirect.hubspot.com/cta/redirect/7215323/b292138e-f940-4d8b-9b09-9923cbecd4d2)   One of the best products on the global market using hypromellose technology and bearing all the previous features is Lyfe Group’s [AR-CAPS](https://capscanada.com/products/acid-resistant-capsules/)®. These gastric acid-resistant and cost-effective hard capsules prevent drug release into the stomach, making them a quality choice for a wide range of enteric pharmaceutical applications. AR-CAPS® release the medicine by disintegrating in the duodenum for intestinal absorption, and are especially suitable for the delivery of probiotic and enzymatic formulations. And one of the company's best added values is that costly and complex enteric coating processes are completely eliminated. As you have noticed, probiotics have a whole development behind them that allows them to be beneficial to health, without causing harmful effects on the digestive system. And although the market is full of these types of products, not all of them comply with the appropriate technology.  If you are looking for a probiotic formulation, bear in mind that quality must be the priority. In addition, look for an empty capsule supplier that carries a wide range of sizes that can be fully customized to align with your brand aesthetics and achieve maximum recognition and impact.    [![Contact Us](https://no-cache.hubspot.com/cta/default/7215323/7f37dd4c-36a6-44d0-a1d4-56b2c007cad6.png)](https://cta-redirect.hubspot.com/cta/redirect/7215323/7f37dd4c-36a6-44d0-a1d4-56b2c007cad6) CapsCanada is proudly part of [Lyfe Group](https://lyfegroup.com/), a global organization specializing in life sciences solutions for the nutraceutical and pharmaceutical markets. Leveraging capsule manufacturing excellence, technical guidance, and end-to-end supply coordination, Lyfe Group supports brands in developing innovative health products for global distribution. Topics: [AR-CAPS®](https://blog.lyfegroup.com/tag/ar-caps) ## Related blogs [![AR-CAPS® vs K-CAPS®: Key and uses cases | CapsCanada ](https://blog.lyfegroup.com/hubfs/image-blog-acid-resistant-vs-delayed-release-capsules-key-differences-and-use-cases.jpg)](https://blog.lyfegroup.com/ar-caps-vs-k-caps-key-and-uses-cases-capscanada) ### [Acid-Resistant vs. Delayed-Release Capsules: Key Differences and Use Cases](https://blog.lyfegroup.com/ar-caps-vs-k-caps-key-and-uses-cases-capscanada) The human gastrointestinal tract is a complex, dynamic system with varying pH levels that presents unique challenges to... [Read More](https://blog.lyfegroup.com/ar-caps-vs-k-caps-key-and-uses-cases-capscanada) [![](https://blog.lyfegroup.com/hubfs/Probiotics%20A%20current%20market%20trend.png)](https://blog.lyfegroup.com/probiotics-are-a-current-market-trend) ### [Probiotics: A current market trend](https://blog.lyfegroup.com/probiotics-are-a-current-market-trend) The World Health Organization defines probiotics as live microorganisms that, when administered, confer a health... [Read More](https://blog.lyfegroup.com/probiotics-are-a-current-market-trend) [![enteric-coated-capsules-option-for-product-development](https://blog.lyfegroup.com/hubfs/enteric-coated-capsules-option-for-product-development.png)](https://blog.lyfegroup.com/enteric-coated-capsules-option-for-product-development) ### [Why Enteric Coated Capsules May Be The Best Option For Your Product Development](https://blog.lyfegroup.com/enteric-coated-capsules-option-for-product-development) Oral delivery is frequently regarded as the preferable route of administration for pharmaceuticals. [Many oral drugs are...](https://drug-dev.com/capsule-technology-enteric-capsule-drug-delivery-technology-achieving-protection-without-coating/) [Read More](https://blog.lyfegroup.com/enteric-coated-capsules-option-for-product-development) [![Gastric acid resistant capsules act by presenting a stable environment on an extreme acid like the stomach.](https://blog.lyfegroup.com/hubfs/52-mini-portada.jpg)](https://blog.lyfegroup.com/acid-resistant-capsules-discover-how-they-work) ### [Acid Resistant Capsules: Discover How They Work](https://blog.lyfegroup.com/acid-resistant-capsules-discover-how-they-work) Acid resistant capsules prevent formulations from being released in the stomach. These types of capsules have an... [Read More](https://blog.lyfegroup.com/acid-resistant-capsules-discover-how-they-work) [![How to facilitate proper absorption of acid-resistant Capsules](https://blog.lyfegroup.com/hubfs/acid-resistant%20capsules-1.jpg)](https://blog.lyfegroup.com/probiotics-and-acid-resistant-capsules-how-to-facilitate-proper-absorption) ### [Probiotics and acid-resistant capsules: how to facilitate proper absorption](https://blog.lyfegroup.com/probiotics-and-acid-resistant-capsules-how-to-facilitate-proper-absorption) Many people take probiotics as an extra measure to help their bodies get the nutrients they need for a healthier life.... [Read More](https://blog.lyfegroup.com/probiotics-and-acid-resistant-capsules-how-to-facilitate-proper-absorption) [![Probiotics: Hard-shell capsule solutions for sensitive compounds](https://blog.lyfegroup.com/hubfs/5-mini-portada.jpg)](https://blog.lyfegroup.com/probiotics-hard-shell-capsule-solutions-for-sensitive-compounds) ### [Probiotics: Hard-shell capsule solutions for sensitive compounds](https://blog.lyfegroup.com/probiotics-hard-shell-capsule-solutions-for-sensitive-compounds) Delivery of drugs and dietary supplements formulated with sensitive compounds can be challenging, particularly if the... 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